L-arginine

Studied for: Erectile Dysfunction

Erectile Dysfunction

What the research found

In that trial, 74% of participants improved their ED severity category. In a double-blind trial evaluating 6 g daily over three months in vasculogenic ED, L-arginine significantly increased IIEF-6 scores in overall cohorts (p < 0.0001) as well as peak systolic velocity (PSV) on dynamic duplex ultrasound

Dose used in studies

2.5 to 6 g daily

Side effects reported

mild dyspepsia, nausea

References

Menafra2022, Menafra2022

Menafra D, et al. Long-term high-dose l-arginine supplementation in patients with vasculogenic erectile dysfunction: a multicentre, double-blind, randomized, placebo-controlled clinical trial. J Endocrinol Invest. 2022;45(5):941–961. doi:10.1007/s40618-021-01704-3.

Not medical advice

Trials are run on specific people, for specific reasons, over a set period. Your medications, conditions and bloodwork can change what is safe for you. Ask a doctor or pharmacist before starting.