Saffron
Studied for: Depression · Erectile Dysfunction · Insomnia
Depression
What the research found
(Crocus sativus): Multiple clinical trials show it outperforms placebo and matches the efficacy of some standard antidepressants. Mechanism: Modulates monoamine neurotransmitters and increases BDNF.
Dose used in studies
30 mg daily
Side effects reported
mild nausea
References
Not yet listed
Erectile Dysfunction
What the research found
(Crocus sativus): Systematic reviews suggest saffron improves erectile and orgasmic function, particularly for men experiencing antidepressant-induced sexual dysfunction.
Dose used in studies
30 mg daily
Side effects reported
mild nausea
References
Not yet listed
Insomnia
What the research found
Recent clinical studies on older adults (ages 55 to 85) taking standardized saffron daily for four weeks found notable benefits. Take a 14 mg to 28 mg dose roughly 1 hour before sleep to support evening melatonin production and calmness.
Dose used in studies
30 mg daily
Side effects reported
mild nausea
References
Not yet listed
Not medical advice
Trials are run on specific people, for specific reasons, over a set period. Your medications, conditions and bloodwork can change what is safe for you. Ask a doctor or pharmacist before starting.